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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
8 DPC

11 matching records from 11 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Tbx5  T-box 5  
Results  Reference
1*J:173839 Bertrand N, Roux M, Ryckebusch L, Niederreither K, Dolle P, Moon A, Capecchi M, Zaffran S, Hox genes define distinct progenitor sub-domains within the second heart field. Dev Biol. 2011 May 15;353(2):266-74
1*J:56093 Bruneau BG, Logan M, Davis N, Levi T, Tabin CJ, Seidman JG, Seidman CE, Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome. Dev Biol. 1999 Jul 1;211(1):100-8
1*J:64882 Christoffels VM, Habets PE, Franco D, Campione M, de Jong F, Lamers WH, Bao ZZ, Palmer S, Biben C, Harvey RP, Moorman AF, Chamber formation and morphogenesis in the developing mammalian heart [published erratum appears in Dev Biol 2000 Sep 1;225(1):266]. Dev Biol. 2000 Jul 15;223(2):266-78
1*J:85728 Hochgreb T, Linhares VL, Menezes DC, Sampaio AC, Yan CY, Cardoso WV, Rosenthal N, Xavier-Neto J, A caudorostral wave of RALDH2 conveys anteroposterior information to the cardiac field. Development. 2003 Nov;130(22):5363-74
1J:127596 Klaus A, Saga Y, Taketo MM, Tzahor E, Birchmeier W, Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis. Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18531-6
1*J:63131 Liberatore CM, Searcy-Schrick RD, Yutzey KE, Ventricular expression of tbx5 inhibits normal heart chamber development. Dev Biol. 2000 Jul 1;223(1):169-80
1J:317819 Minguillon C, Nishimoto S, Wood S, Vendrell E, Gibson-Brown JJ, Logan MP, Hox genes regulate the onset of Tbx5 expression in the forelimb. Development. 2012 Sep;139(17):3180-8
1J:185712 Prall OW, Menon MK, Solloway MJ, Watanabe Y, Zaffran S, Bajolle F, Biben C, McBride JJ, Robertson BR, Chaulet H, Stennard FA, Wise N, Schaft D, Wolstein O, Furtado MB, Shiratori H, Chien KR, Hamada H, Black BL, Saga Y, Robertson EJ, Buckingham ME, HarveyRP, An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation. Cell. 2007 Mar 9;128(5):947-59
1J:132815 Ryckebusch L, Wang Z, Bertrand N, Lin SC, Chi X, Schwartz R, Zaffran S, Niederreither K, Retinoic acid deficiency alters second heart field formation. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2913-8
1*J:144407 Vong L, Bi W, O'Connor-Halligan KE, Li C, Cserjesi P, Schwarz JJ, MEF2C is required for the normal allocation of cells between the ventricular and sinoatrial precursors of the primary heart field. Dev Dyn. 2006 Jul;235(7):1809-21
1J:339247 Zhang C, Li Y, Cao J, Yu B, Zhang K, Li K, Xu X, Guo Z, Liang Y, Yang X, Yang Z, Sun Y, Kaartinen V, Ding K, Wang J, Hedgehog signalling controls sinoatrial node development and atrioventricular cushion formation. Open Biol. 2021 Jun;11(6):210020

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory